CHICAGO — Josh Giddey had 17 points, nine rebounds and seven assists, and the Chicago Bulls beat the struggling Charlotte Hornets 109-95 on Friday night. Ayo Dosunmu scored 19 points as Chicago bounced back from two straight losses. Coby White added 18 points. Giddey and Dosunmu each hit three 3-pointers for the Bulls, who led almost the entire way, sending the Hornets to their 13th loss in 16 games. Brandon Miller led Charlotte with 21 points, and Mark Williams had 15. Miles Bridges added 14 points and nine rebounds after missing 10 games because of a bruised right knee. Former Bull Taj Gibson got a standing ovation when he checked into the game with about a minute remaining. Takeaway Hornets: Though they're getting healthier after being hit hard by injuries, the Hornets can't get star guard LaMelo Ball back soon enough. The NBA's third-leading scorer missed his seventh straight game because of a strained left calf. Bulls: The Bulls were aggressive, took control early and withstood several minor pushes on the way to a rather easy win. Chicago Bulls guard Ayo Dosunmu, left, guards Charlotte Hornets forward Miles Bridges during the first half of an NBA basketball game Friday, Dec. 13, 2024, in Chicago. Credit: AP/Erin Hooley Key moment Bulls guard Lonzo Ball had the crowd roaring late in the first half when he hustled to track down a loose ball near midcourt and connected with Zach LaVine for a thunderous alley-oop dunk. After Miller hit a 13-footer for Charlotte, Dosunmu drove for a layup. Bridges got called for a technical after missing on a drive. LaVine hit the free throw to make it 59-42 with 18 seconds left but got called for a travel, leading to a floater for Miller at the halftime buzzer that cut the lead to 15. Key stat The Bulls blocked a season-high 11 shots, with Jalen Smith matching a career best by rejecting five. He also had 11 points and 11 rebounds. Up next The Hornets host Philadelphia on Monday, while the Bulls visit Toronto that night.Bucks get second crack at NBA Cup semis vs. Trae Young, Hawks
Jega Tasks Politicians To Emulate Nigeria’s Founding FathersWinnebago was one of the first major American RV manufacturers to embrace the van life and overlanding trends when it launched the Mercedes-Benz Sprinter 4x4-based Revel , after sending out market feelers with the van. Believe it or not, the Revel was less than US$135,000 back then, a price that's since soared to nearly double: over $254K for the 2025 Revel. Winnebago rolls that pricing back a bit with the new/old 2025 Revel Sport, a lighter version of the Revel that offers more buyer flexibility. But is it cheap enough to keep the off-road van life party rolling onward into the future? Winnebago updated the original Revel for the 2025 model year , and the new Sport model carries over the specs of the outgoing Revel while pulling the official MSRP back to previous-year levels. Winnebago, of course, advertises it as an all-new model, but the new model appears to be the product of a large leftover stock of older Revel vans or components. Regardless of the Sport's origins, it's nice to have options as a consumer, especially when putting down six figures' worth of hard-earned cash. Given how dramatically the price of the Revel has risen in just seven years, it's also nice to see it rolling back in the other direction. Ultimately, the two-model lineup gives buyers more flexibility in finding a van to fit their life and budget. And if it still looks overpriced, there's always the . Winnebago's big brag for the standard 2025 Revel 44E is a full week's worth of off-grid capabilities that make it a headliner in the new Backcountry Series. That package centers around an 8.4-kWh Lithionics lithium-ion Winnebago Power Max system with EcoFlow control hub and 3,600-W inverter. The Sport goes back to the 4.1-kWh Lithionics lithium battery system and smaller 2,000-W inverter the Revel featured before the off-grid "Backcountry Series" update. The Sport complements that battery with 215 watts of roof-mounted solar, but buyers will have to forego the full estimated week of power autonomy they'd get with the upgraded non-Sport Revel. Since the Revel Sport has no need to live up to claims of seven-day autonomy, its fresh water capacity rolls back to previous levels with a 91-L tank, down from the 132.5 liters of the 2025 Revel 44E. The gray tank handles the same 79.5 liters. The Sport floor plan is labeled the 44N instead of 44E but is laid out the same as the Revel has always been, starting with the rear bed that power-lifts to the roof to clear out a full gear storage garage during the drive. That bed does not share the "WinnSleep" suspension sleep system upgrade of the 2025 Revel 44E, however. It seems Winnebago could have manipulated the price lower by swapping the power lift system out for a manual lift or fixed bed, but since the Revel Sport is really just the old Revel, it didn't do anything of the sort. Moving forward, the floor plan continues with the wet bathroom with removable shelving, shower and cassette toilet; kitchen block with stainless steel sink, portable single-burner induction cooker and 85-L compressor fridge/freezer; and front lounge with two-seat bench, removable table and swivel cab seats. If you're still not convinced this is an old Revel disguised as a new Sport, note the familiar older features throughout, starting with the low-back two-seat rear bench in place of the taller, separable individual rear seats on the 2025 Revel 44E, the oval dining table instead of the newer rectangular table, the removable kitchen counter extension instead of the drawer, and the old bathroom door design in place of the separate French-style doors. That's not a knock on any of those features, as they were all standards previously, just worth noting as points of differentiation. Of course, Winnebago still debuted the Revel Sport as part of the new model contingent in its "bold and innovative" MY2025 lineup at this year's Hershey RV Show back in September. We suppose bringing the price down is a "bold" move anyone can appreciate, even if no one would call the Sport's $210,570 base price a bargain-basement steal. It's certainly a lower ceiling from which to start the negotiations. Like the 44E, the 2025 Revel Sport 44N is built on a 19.5-foot (5.9-m) Mercedes-Benz Sprinter AWD 144 with 2.0-liter four-cylinder turbo-diesel and nine-speed automatic transmission. It comes loaded with driver-assistance tech, including Distronic Plus adaptive cruise control, active lane keeping assist, active braking assist and driver attention assist. Winnebago can shod the four wheels in optional BFGoodrich KO2 all-terrain tires for those looking to up their traction. Source:
Lewis 8-11 1-4 17, Lesburt 3-5 3-4 11, Lilly 5-13 6-7 21, Wrisby-Jefferson 1-3 1-2 3, Cooley 4-6 4-4 13, Erold 5-9 3-3 16, Jenkins 0-2 0-1 0, DeGraaf 1-1 0-0 2, Klores 0-0 0-0 0. Totals 27-50 18-25 83. Javascript is required for you to be able to read premium content. Please enable it in your browser settings.Middle East latest: Syrians celebrate Assad's fall as US seeks a peaceful political transition
Four Ups, Four Downs: Bryce Young Improvement, Jameson Williams Big Gains, Russell Wilson Extending PlaysNone
There are many reasons why ice hockey is on track to be a fast-growing sport in Palm Beach County, including plans for new ice facilities and more hockey events.Report: Chargers expect WR Ladd McConkey, LB Khalil Mack to play vs. Ravens
Get ready for a college football bowl season like you’ve never seen. It’s the first year of the expanded 12-team College Football Playoff to determine the national champion, with first-round games kicking off Friday, December 20. In the new format, the top four conference champions (Oregon, Georgia, Arizona State and Boise State) receive a first-round bye and automatic entry into the quarterfinals. The remaining eight teams play in the four-game first round, with matchups held at the home stadiums of the higher-ranked participants. The “New Year’s Six” bowls serve as the quarterfinals and semifinals, with the national championship decided Monday, January 20, at Mercedes-Benz Stadium in Atlanta. Of course, there’s still plenty of college football postseason action through early January that doesn’t involve the national championship chase. The parade of bowl games begins Saturday, December 14, with the Cricket Celebration Bowl in Atlanta. A great tradition continues in Landover, Maryland, as the Navy Midshipmen take on the Army Black Knights Saturday on CBS at 3/2c. Later on Saturday, the Heisman Trophy is presented to the season’s most outstanding player in a ceremony on ESPN at 8/7c. Finalists are Oregon QB Dillon Gabriel, Colorado WR/CB Travis Hunter, Boise State RB Ashton Jeanty (pictured above) and Miami QB Cam Ward. Here’s your complete lineup of College Football Playoff games and other bowl matchups: All times Eastern/Central. Friday, December 20 No. 10 Indiana at No. 7 Notre Dame, ABC/ESPN, 8/7c Saturday, December 21 No. 11 SMU at No. 6 Penn State, noon/11a c, TNT/Max No. 12 Clemson at No. 5 Texas, 4/3c, TNT/Max No. 9 Tennessee at No. 8 Ohio State, 8/7c, ABC/ESPN Tuesday, December 31 Vrbo Fiesta Bowl (Glendale, Arizona): TBA vs. No. 3 Boise State, (ESPN) Wednesday, Jan. 1 Chick-fil-A Peach Bowl (Atlanta): TBA vs. No. 4 Arizona State, 1/noon c, ESPN Rose Bowl (Pasadena, California): TBA vs. No. 1 Oregon, 5/4c, ESPN Allstate Sugar Bowl (New Orleans): TBA vs. No. 2 Georgia, 8:45/7:45c, ESPN Thursday, January 9 Capital One Orange Bowl (Miami, Florida): TBA vs. TBA, 7:30/6:30c, ESPN Friday, January 10 Goodyear Cotton Bowl Classic (Arlington, Texas): TBA vs. TBA, 7:30/6:30c, ESPN Monday, January 20 National Championship (Atlanta): TBA vs. TBA, 7:30/6:30c, ESPN Saturday, December 14 Cricket Celebration Bowl (Atlanta): Jackson State vs. South Carolina State, noon/11a c, ABC IS4S Salute to Veterans Bowl (Montgomery, Alabama): South Alabama vs. Western Michigan, 9/8c, ESPN Tuesday, December 17 Scooter’s Coffee Frisco Bowl (Frisco, Texas): Memphis vs. West Virginia, 9/8c, ESPN Wednesday, December 18 Boca Raton Bowl (Boca Raton, Florida): Western Kentucky vs. James Madison, 5:30/4:30c, ESPN Art of Sport LA Bowl (Inglewood, California): Cal vs. UNLV, 9/8c, ESPN Thursday, December 19 R+L Carriers New Orleans Bowl (New Orleans): Georgia Southern vs. Sam Houston, 7/6c, ESPN2 Friday, December 20 StaffDNA Cure Bowl (Orlando, Florida): Ohio vs. Jacksonville State, noon/11a c, ESPN Union Home Mortgage Gasparilla Bowl (Tampa, Florida): 3:30/2:30c, ESPN Monday, December 23 Myrtle Beach Bowl (Conway, South Carolina): Coastal Carolina vs. UTSA, 11a/10a c, ESPN Famous Idaho Potato Bowl (Boise, Idaho): Northern Illinois vs. Fresno State, 2:30/1:30c, ESPN Tuesday, December 24 Hawai’i Bowl (Honolulu): South Florida vs. San José State, 8/7c, ESPN Thursday, December 26 GameAbove Sports Bowl (Detroit): Pittsburgh vs. Toledo, 2/1xc, ESPN Rate Bowl (Phoenix): Rutgers vs. Kansas State, 5:30/4:30c, ESPN 68 Ventures Bowl (Mobile, Alabama): Arkansas State vs. Bowling Green, 9/8c, ESPN Friday, December 27 Lockheed Martin Armed Forces Bowl (Fort Worth, Texas): Oklahoma vs. Navy, noon/11a c, ESPN Birmingham Bowl (Birmingham, Alabama): Georgia Tech vs. Vanderbilt, 3:30/2:30c, ESPN AutoZone Liberty Bowl (Memphis, Tennessee): Texas Tech vs. Arkansas, 7/6c, ESPN DirecTV Holiday Bowl (San Diego): Syracuse vs. Washington State, 8/7c, Fox SRS Distribution Las Vegas Bowl (Las Vegas): Texas A&M vs. USC, 10:30/9:30c, ESPN Saturday, December 28 Wasabi Fenway Bowl (Boston): UConn vs. North Carolina, 11a/10a c, ESPN Bad Boy Mowers Pinstripe Bowl (Bronx, New York): Boston College vs. Nebraska, Noon/11a c, ABC Isleta New Mexico Bowl (Albuquerque, New Mexico): Louisiana vs. TCU, 2:15/1:15c, ESPN Pop-Tarts Bowl (Orlando, Florida): Iowa State vs. Miami, 3:30/2:30c, ABC Snoop Dogg Arizona Bowl (Tucson, Arizona): Miami (Ohio) vs. Colorado State, 4:30/3:30c, The CW Go Bowling Military Bowl (Annapolis, Maryland): East Carolina vs. NC State, 5:45/4:45c, ESPN Valero Alamo Bowl (San Antonio): BYU vs. Colorado, 7:30/6:30c, ABC Radiance Technologies Independence Bowl (Shreveport, Louisiana): Marshall vs. Army, 9:15/8:15c, ESPN Monday, December 30 TransPerfect Music City Bowl (Nashville, Tennessee): Iowa vs. Missouri, 2:30/1:30c, ESPN Tuesday, December 31 ReliaQuest Bowl (Tampa, Florida): Alabama vs. Michigan, noon/11a c, ESPN Tony the Tiger Sun Bowl (El Paso, Texas): Louisville vs. Washington, 2/1c, CBS Cheez-It Citrus Bowl (Orlando, Florida): South Carolina vs. Illinois, 3/2c, ABC Kinder’s Texas Bowl (Houston): Baylor vs. LSU, 3:30/2:30c, ESPN Thursday, January 2 TaxSlayer Gator Bowl (Jacksonville, Florida): Duke vs. Ole Miss, 7:30/6:30c, ESPN Friday, January 3 SERVPRO First Responder Bowl (Dallas): North Texas vs. Texas State, 4/3c, ESPN Duke’s Mayo Bowl (Charlotte, North Carolina): Minnesota vs. Virginia Tech, 7:30/6:30c, ESPN Saturday, January 4 Bahamas Bowl (Nassau, Bahamas): Buffalo vs. Liberty, 11a/10a c, ESPN2 More Headlines:TORONTO, Dec. 13, 2024 (GLOBE NEWSWIRE) -- Edesa Biotech, Inc. (Nasdaq:EDSA), a clinical-stage biopharmaceutical company focused on developing host-directed therapeutics for immuno-inflammatory diseases, today reported financial results for the fiscal year ended September 30, 2024 and provided an update on its business. During the fiscal year, the company pivoted the in-house development of its anti-TLR4 drug candidate, EB05 (paridiprubart), to a U.S. government-funded study investigating novel threat-agnostic host-directed therapeutics in patients with Acute Respiratory Distress Syndrome (ARDS). Given this opportunity, Edesa is also amending a development and drug manufacturing project for the same asset that is supported by the Government of Canada. The company said that the goal is to maximize synergies between the two government-funded projects. For its anti-CXCL10 program, Edesa intends to manufacture EB06 and submit related data to the U.S. Food and Drug Administration as part of an investigational new drug (IND) application. The manufacturing of clinical-grade drug batches and initiation of the patient enrollment is subject to funding. Edesa anticipates topline results for this Phase 2 study could be available within as few as 12 to 18 months following regulatory clearance in the U.S. The study is currently approved in Canada. “This year, Edesa maintained its momentum despite the headwinds in the drug development sector, and we once again validated our TLR4 technology with a third competitive government award,” said Par Nijhawan, MD, Chief Executive Officer of Edesa Biotech. “I have maintained my strategic support financially and I believe that our team can continue to advance and expand our development pipeline and partnerships.” Edesa's Chief Financial Officer Stephen Lemieux reported that financial results for the fiscal year benefited from prudent use of working capital and effective financial management, including a more than 20% decrease in operating expenses. “Following the end of the fiscal year, we strengthened our balance sheet, and with two governments now funding the advancement of our anti-TLR4 technology, we have improved our position for future financing, potential strategic arrangements as well as other opportunities to advance our pipeline.” Financial Results for the Fiscal Year Ended September 30, 2024 Total operating expenses decreased by $2.2 million to $7.0 million for the year ended September 30, 2024 compared to $9.2 million for the prior year: Research and development expenses decreased by $1.9 million to $2.9 million for the year ended September 30, 2024 compared to $4.8 million for the prior year primarily due to decreased external research expenses related to the company’s completed dermatitis study and a reduction in labor costs and noncash share-based compensation, which were partially offset by an increase in expenses related to manufacturing of paridiprubart. General and administrative expenses decreased by $0.3 million to $4.1 million for year ended September 30, 2024 compared to $4.4 million for the prior year primarily due to a decrease in noncash share-based compensation, which was partially offset by an increase salaries and related costs. Total other income was unchanged at $0.8 million for the years ended September 30, 2024 and September 30, 2023 as a $0.1 million increase in reimbursement funding from the Canadian government's Strategic Innovation Fund was offset by a $0.1 million decrease in interest income. For the year ended September 30, 2024, Edesa reported a net loss of $6.2 million, or $1.93 per common share, compared to a net loss of $8.4 million, or $2.93 per common share, for the year ended September 30, 2023. Working Capital At September 30, 2024, Edesa had cash and cash equivalents of $1.0 million and negative working capital of $0.2 million. Subsequent to the fiscal year end, the company received $1.5 million in gross proceeds under a securities purchase agreement with an entity affiliated with Edesa’s Chief Executive Officer and Founder, and $0.6 million in net proceeds, after deducting sales agent commissions, from common shares sold under an at-the-market offering program. Calendar Edesa management plans to participate in one-on-one meetings during JP Morgan week, which begins on January 13, 2025, in San Francisco, California. Attendees interested in meeting with management can request meetings through the conference organizers or by contacting Edesa directly at investors@edesabiotech.com . About Edesa Biotech, Inc. Edesa Biotech, Inc. (Nasdaq: EDSA) is a clinical-stage biopharmaceutical company developing innovative ways to treat inflammatory and immune-related diseases. Its clinical pipeline is focused on two therapeutic areas: Medical Dermatology and Respiratory. In Medical Dermatology, Edesa is developing EB06, an anti-CXCL10 monoclonal antibody candidate, as therapy for vitiligo, a common autoimmune disorder that causes skin to lose its color in patches. Its medical dermatology assets also include EB01 (1.0% daniluromer cream), a Phase 3-ready asset developed for use as a potential therapy for moderate-to-severe chronic Allergic Contact Dermatitis (ACD), a common occupational skin condition. The company’s most advanced Respiratory drug candidate is EB05 (paridiprubart), which is being evaluated in a U.S. government-funded platform study as a treatment for Acute Respiratory Distress Syndrome (ARDS), a life-threatening form of respiratory failure. The EB05 program has been the recipient of two funding awards from the Government of Canada to support the further development of this asset. In addition to EB05, Edesa is preparing an investigational new drug application (IND) in the United States for EB07 (paridiprubart) to conduct a future Phase 2 study in patients with pulmonary fibrosis. Sign up for news alerts . Connect with us on X and LinkedIn . Edesa Forward-Looking Statements This press release may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "plan," "estimate," "expect," "intend," "may," "will," "would," "could," "should," "might," "potential," or "continue" and variations or similar expressions, including statements related to: Edesa’s ability to pivot the in-house development of its anti-TLR4 drug candidate; the company’s plans to amend its contribution agreement with the Government of Canada; the company’s goal to maximize synergies between two government-funded projects; Edesa plans to manufacture EB06 and submit related data to the FDA as part of an IND application; the company’s plans to manufacture clinical-grade drug and initiate patient enrollment; the company’s plans to finance clinical and manufacturing activities; the company’s estimate that topline results for its Phase 2 vitiligo study could be available within as few as 12 to 18 months following regulatory clearance; the company’s belief that in 2024 it maintained its momentum despite the headwinds in the drug development sector and once again validated its TLR4 technology with a third competitive government award; the company’s belief that its team can continue to advance and expand its development pipeline and partnerships; the company’s belief that its fiscal year financial results benefited from prudent use of working capital and effective financial management; the company’s belief that with two governments funding the advancement of its anti-TLR4 technology, it has improved its position for future financing, potential strategic arrangements and alternatives as well as other opportunities to advance its pipeline; and the company's timing and plans regarding its clinical studies in general. Readers should not unduly rely on these forward-looking statements, which are not a guarantee of future performance. There can be no assurance that forward-looking statements will prove to be accurate, as all such forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future events to differ materially from the forward-looking statements. Such risks include: the ability of Edesa to obtain regulatory approval for or successfully commercialize any of its product candidates, the risk that access to sufficient capital to fund Edesa's operations may not be available or may be available on terms that are not commercially favorable to Edesa, the risk that Edesa's product candidates may not be effective against the diseases tested in its clinical trials, the risk that Edesa fails to comply with the terms of license agreements with third parties and as a result loses the right to use key intellectual property in its business, Edesa's ability to protect its intellectual property, the timing and success of submission, acceptance and approval of regulatory filings, and the impacts of public health crises. Many of these factors that will determine actual results are beyond the company's ability to control or predict. For a discussion of further risks and uncertainties related to Edesa's business, please refer to Edesa's public company reports filed with the U.S. Securities and Exchange Commission and the British Columbia Securities Commission. All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, Edesa assumes no obligation to update such statements.Democrat Bob Casey concedes to Republican David McCormick in Pennsylvania Senate contest
Cemtrex Announces 1-For-35 Reverse Stock Split
TORONTO, Dec. 13, 2024 (GLOBE NEWSWIRE) -- Edesa Biotech, Inc. EDSA , a clinical-stage biopharmaceutical company focused on developing host-directed therapeutics for immuno-inflammatory diseases, today reported financial results for the fiscal year ended September 30, 2024 and provided an update on its business. During the fiscal year, the company pivoted the in-house development of its anti-TLR4 drug candidate, EB05 (paridiprubart), to a U.S. government-funded study investigating novel threat-agnostic host-directed therapeutics in patients with Acute Respiratory Distress Syndrome (ARDS). Given this opportunity, Edesa is also amending a development and drug manufacturing project for the same asset that is supported by the Government of Canada. The company said that the goal is to maximize synergies between the two government-funded projects. For its anti-CXCL10 program, Edesa intends to manufacture EB06 and submit related data to the U.S. Food and Drug Administration as part of an investigational new drug (IND) application. The manufacturing of clinical-grade drug batches and initiation of the patient enrollment is subject to funding. Edesa anticipates topline results for this Phase 2 study could be available within as few as 12 to 18 months following regulatory clearance in the U.S. The study is currently approved in Canada. "This year, Edesa maintained its momentum despite the headwinds in the drug development sector, and we once again validated our TLR4 technology with a third competitive government award," said Par Nijhawan, MD, Chief Executive Officer of Edesa Biotech. "I have maintained my strategic support financially and I believe that our team can continue to advance and expand our development pipeline and partnerships." Edesa's Chief Financial Officer Stephen Lemieux reported that financial results for the fiscal year benefited from prudent use of working capital and effective financial management, including a more than 20% decrease in operating expenses. "Following the end of the fiscal year, we strengthened our balance sheet, and with two governments now funding the advancement of our anti-TLR4 technology, we have improved our position for future financing, potential strategic arrangements as well as other opportunities to advance our pipeline." Financial Results for the Fiscal Year Ended September 30, 2024 Total operating expenses decreased by $2.2 million to $7.0 million for the year ended September 30, 2024 compared to $9.2 million for the prior year: Research and development expenses decreased by $1.9 million to $2.9 million for the year ended September 30, 2024 compared to $4.8 million for the prior year primarily due to decreased external research expenses related to the company's completed dermatitis study and a reduction in labor costs and noncash share-based compensation, which were partially offset by an increase in expenses related to manufacturing of paridiprubart. General and administrative expenses decreased by $0.3 million to $4.1 million for year ended September 30, 2024 compared to $4.4 million for the prior year primarily due to a decrease in noncash share-based compensation, which was partially offset by an increase salaries and related costs. Total other income was unchanged at $0.8 million for the years ended September 30, 2024 and September 30, 2023 as a $0.1 million increase in reimbursement funding from the Canadian government's Strategic Innovation Fund was offset by a $0.1 million decrease in interest income. For the year ended September 30, 2024, Edesa reported a net loss of $6.2 million, or $1.93 per common share, compared to a net loss of $8.4 million, or $2.93 per common share, for the year ended September 30, 2023. Working Capital At September 30, 2024, Edesa had cash and cash equivalents of $1.0 million and negative working capital of $0.2 million. Subsequent to the fiscal year end, the company received $1.5 million in gross proceeds under a securities purchase agreement with an entity affiliated with Edesa's Chief Executive Officer and Founder, and $0.6 million in net proceeds, after deducting sales agent commissions, from common shares sold under an at-the-market offering program. Calendar Edesa management plans to participate in one-on-one meetings during JP Morgan week, which begins on January 13, 2025, in San Francisco, California. Attendees interested in meeting with management can request meetings through the conference organizers or by contacting Edesa directly at investors@edesabiotech.com . About Edesa Biotech, Inc. Edesa Biotech, Inc. EDSA is a clinical-stage biopharmaceutical company developing innovative ways to treat inflammatory and immune-related diseases. Its clinical pipeline is focused on two therapeutic areas: Medical Dermatology and Respiratory. In Medical Dermatology, Edesa is developing EB06, an anti-CXCL10 monoclonal antibody candidate, as therapy for vitiligo, a common autoimmune disorder that causes skin to lose its color in patches. Its medical dermatology assets also include EB01 (1.0% daniluromer cream), a Phase 3-ready asset developed for use as a potential therapy for moderate-to-severe chronic Allergic Contact Dermatitis (ACD), a common occupational skin condition. The company's most advanced Respiratory drug candidate is EB05 (paridiprubart), which is being evaluated in a U.S. government-funded platform study as a treatment for Acute Respiratory Distress Syndrome (ARDS), a life-threatening form of respiratory failure. The EB05 program has been the recipient of two funding awards from the Government of Canada to support the further development of this asset. In addition to EB05, Edesa is preparing an investigational new drug application (IND) in the United States for EB07 (paridiprubart) to conduct a future Phase 2 study in patients with pulmonary fibrosis. Sign up for news alerts . Connect with us on X and LinkedIn . Edesa Forward-Looking Statements This press release may contain forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements may be identified by the use of words such as "anticipate," "believe," "plan," "estimate," "expect," "intend," "may," "will," "would," "could," "should," "might," "potential," or "continue" and variations or similar expressions, including statements related to: Edesa's ability to pivot the in-house development of its anti-TLR4 drug candidate; the company's plans to amend its contribution agreement with the Government of Canada; the company's goal to maximize synergies between two government-funded projects; Edesa plans to manufacture EB06 and submit related data to the FDA as part of an IND application; the company's plans to manufacture clinical-grade drug and initiate patient enrollment; the company's plans to finance clinical and manufacturing activities; the company's estimate that topline results for its Phase 2 vitiligo study could be available within as few as 12 to 18 months following regulatory clearance; the company's belief that in 2024 it maintained its momentum despite the headwinds in the drug development sector and once again validated its TLR4 technology with a third competitive government award; the company's belief that its team can continue to advance and expand its development pipeline and partnerships; the company's belief that its fiscal year financial results benefited from prudent use of working capital and effective financial management; the company's belief that with two governments funding the advancement of its anti-TLR4 technology, it has improved its position for future financing, potential strategic arrangements and alternatives as well as other opportunities to advance its pipeline; and the company's timing and plans regarding its clinical studies in general. Readers should not unduly rely on these forward-looking statements, which are not a guarantee of future performance. There can be no assurance that forward-looking statements will prove to be accurate, as all such forward-looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future events to differ materially from the forward-looking statements. Such risks include: the ability of Edesa to obtain regulatory approval for or successfully commercialize any of its product candidates, the risk that access to sufficient capital to fund Edesa's operations may not be available or may be available on terms that are not commercially favorable to Edesa, the risk that Edesa's product candidates may not be effective against the diseases tested in its clinical trials, the risk that Edesa fails to comply with the terms of license agreements with third parties and as a result loses the right to use key intellectual property in its business, Edesa's ability to protect its intellectual property, the timing and success of submission, acceptance and approval of regulatory filings, and the impacts of public health crises. Many of these factors that will determine actual results are beyond the company's ability to control or predict. For a discussion of further risks and uncertainties related to Edesa's business, please refer to Edesa's public company reports filed with the U.S. Securities and Exchange Commission and the British Columbia Securities Commission. All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, Edesa assumes no obligation to update such statements. Consolidated Statements of Operations Years Ended September 30, 2024 September 30, 2023 Expenses: Research and development $ 2,881,967 $ 4,794,549 General and administrative 4,132,777 4,428,209 Loss from operations (7,014,744 ) (9,222,758 ) Other Income (Loss): Reimbursement grant income 698,277 581,039 Other income (loss) 147,222 268,104 Income tax expense 800 800 Net loss (6,170,045 ) (8,374,415 ) Exchange differences on translation (27,965 ) (1,046 ) Net comprehensive loss $ (6,198,010 ) $ (8,375,461 ) Weighted average number of common shares 3,197,423 2,858,929 Loss per common share - basic and diluted $ (1.93 ) $ (2.93 ) Consolidated Balance Sheets September 30, 2024 September 30, 2023 Assets: Cash and cash equivalents $ 1,037,320 $ 5,361,397 Other current assets 638,302 1,075,455 Non-current assets 2,138,360 2,453,585 Total Assets $ 3,813,982 $ 8,890,437 Liabilities and shareholders' equity: Current liabilities $ 1,832,827 $ 1,821,864 Non-current liabilities - 19,773 Shareholders' equity 1,981,155 7,048,800 Total liabilities and shareholders' equity $ 3,813,982 $ 8,890,437 Consolidated Statements of Cash Flows Years Ended September 30, 2024 September 30, 2023 Cash flows from operating activities: Net loss $ (6,170,045 ) $ (8,374,415 ) Adjustments for non-cash items 708,775 1,429,928 Change in working capital items 571,065 308,004 Net cash used in operating activities (4,890,205 ) (6,636,483 ) Net cash provided by financing activities 592,031 4,830,111 Effect of exchange rate changes on cash and cash equivalents (25,903 ) 76,850 Net change in cash and cash equivalents (4,324,077 ) (1,729,522 ) Cash and cash equivalents, beginning of year 5,361,397 7,090,919 Cash and cash equivalents, end of year $ 1,037,320 $ 5,361,397 © 2024 Benzinga.com. Benzinga does not provide investment advice. All rights reserved.No. 2 Ohio State takes control in the 2nd half and runs over No. 5 Indiana 38-15
NEW YORK, Dec. 19, 2024 (GLOBE NEWSWIRE) -- Esusu , the fintech platform leveraging rental data to close the racial wealth gap, released its 2024 Year in Review Data Report today, showcasing record-breaking achievements in advancing financial inclusion and reducing housing barriers for working families. The data reveals the creation of 189,438 new credit scores and over $46.9 billion in capital unlocked for renters via new credit tradelines. Esusu’s latest data demonstrates an average credit score increase of +45 points for renters reporting with Esusu throughout the length of enrollment. Over 12% of renters on the Esusu platform progressed from subprime to prime credit scores, a life-changing improvement in credit that helped increase financial stability and access to lines of credit with more favorable terms. As of September 2024, Esusu renters have experienced the following positive outcomes: 257,438 auto loans accessed, totaling more than $8.6 billion 84,827 student loans accessed, totaling more than $2 billion 63,232 mortgages accessed, totaling more than $29.1 billion “In a year marked by increased economic uncertainty, Esusu remains committed to empowering renters nationwide with access to quality financial resources,” said Samir Goel and Wemimo Abbey, Co-Founders of Esusu. “Through on-time rent reporting, families have unlocked critical pathways to economic mobility—gaining access to cars, education, homeownership, and other essential resources that drive wealth creation and resilience in today’s evolving landscape. With the launch of myEsusu , we are poised to further expand these opportunities and build a more equitable financial future for all.” In an effort to reach more renters, Esusu recently launched myEsusu, a credit-building membership designed to empower renters by removing financial barriers and providing access to wealth-building opportunities, available on the free Esusu app ( iOS and Android ). Until now, the Esusu platform has only been available to renters living in a network of 250,000+ Esusu-participating properties across the United States (the Esusu Community Network). For millions of other renters, myEsusu is designed to be the most affordable and robust financial membership to build credit in the market. For more information, visit www.esusurent.com About Esusu Esusu is the leading financial technology platform that leverages data solutions to empower residents and improve property performance. Esusu's rent reporting platform captures rental payment data and reports it to credit bureaus to boost credit scores. This allows renters to build and establish their credit scores while helping property owners mitigate against initiating evictions, powered by differentiated data and insights. Founded in 2018, Esusu reaches over 5 million rental units across all 50 states in the United States. Learn more at www.esusurent.com and follow us on Instagram @myesusu and on Twitter @getesusu. Media Contact: Small Girls PR esusu@smallgirlspr.comJoe Biden begins final White House holiday season with turkey pardons for 'Peach' and 'Blossom' WASHINGTON (AP) — President Joe Biden has kicked off his final holiday season at the White House, issuing the traditional reprieve to two turkeys who will bypass the Thanksgiving table to live out their days in Minnesota. The president welcomed 2,500 guests under sunny skies as he cracked jokes about the fates of “Peach” and “Blossom.” He also sounded wistful tones about the last weeks of his presidency. Separately, first lady Jill Biden received the delivery of the official White House Christmas tree. And the Bidens are traveling to New York later Monday for an early holiday celebration with members of the Coast Guard. Bah, humbug! Vandal smashes Ebenezer Scrooge's tombstone used in 'A Christmas Carol' movie LONDON (AP) — If life imitates art, a vandal in the English countryside may be haunted by The Ghost of Christmas Yet to Come. Police in the town of Shrewsbury are investigating how a tombstone at the fictional grave of Ebenezer Scrooge was destroyed. The movie prop used in the 1984 adaption of Charles Dickens' “A Christmas Carol” had become a tourist attraction. The film starred George C. Scott as the cold-hearted curmudgeon who is visited by three ghosts on Christmas Eve who show him what will become of his life if he doesn’t become a better person. West Mercia Police say the stone was vandalized in the past week. Megachurch founder T.D. Jakes suffers health incident during sermon at Dallas church DALLAS (AP) — The founder of Dallas-based megachurch The Potter's House, Bishop T.D. Jakes, was hospitalized after suffering what the church called a “slight health incident.” Jakes was speaking to churchgoers after he sat down and began trembling as several people gathered around him Sunday at the church. Jakes' daughter Sarah Jakes Roberts and her husband Touré Roberts said in a statement on social media late Sunday that Jakes was improving. The 67-year-old Jakes founded the non-denominational The Potter's House in 1996 and his website says it now has more than 30,000 members with campuses in Fort Worth and Frisco, Texas; and in Denver. Warren Buffett gives away another $1.1B and plans for distributing his $147B fortune after his death OMAHA, Neb. (AP) — Investor Warren Buffett renewed his Thanksgiving tradition of giving by announcing plans Monday to hand more than $1.1 billion of Berkshire Hathaway stock to four of his family's foundations, and he offered new details about who will be handing out the rest of his fortune after his death. Buffett has said previously that his three kids will distribute his remaining $147.4 billion fortune in the 10 years after his death, but now he has also designated successors for them because it’s possible that Buffett’s children could die before giving it all away. Buffett said he has no regrets about his decision to start giving away his fortune in 2006. At the crossroads of news and opinion, 'Morning Joe' hosts grapple with aftermath of Trump meeting The reaction of those who defended “Morning Joe” hosts Joe Scarborough and Mika Brzezinski for meeting with President-elect Trump sounds almost quaint in the days of opinionated journalism. Doesn't it makes sense, they said, for hosts of a political news show to meet with such an important figure? But given how “Morning Joe” has attacked Trump, its viewers felt insulted. Many reacted quickly by staying away. It all reflects the broader trend of opinion crowding out traditional journalist in today's marketplace, and the expectations that creates among consumers. By mid-week, the show's audience was less than two-thirds what it has typically been this year. Pop star Ed Sheeran apologizes to Man United boss Ruben Amorim for crashing interview MANCHESTER, England (AP) — British pop star Ed Sheeran has apologized to Ruben Amorim after inadvertently interrupting the new Manchester United head coach during a live television interview. Amorim was talking on Sky Sports after United’s 1-1 draw with Ipswich on Sunday when Sheeran walked up to embrace analyst Jamie Redknapp. The interview was paused before Redknapp told the pop star to “come and say hello in a minute.” Sheeran is a lifelong Ipswich fan and holds a minority stake in the club. He was pictured celebrating after Omari Hutchinson’s equalizing goal in the game at Portman Road. A desert oasis outside of Dubai draws a new caravan: A family of rodents from Argentina AL QUDRA LAKES, United Arab Emirates (AP) — A desert oasis hidden away in the dunes in the far reaches of skyscraper-studded Dubai has drawn a surprising new set of weary world travelers: a pack of Argentinian rodents. A number of Patagonian mara, a rabbit-like mammal with long legs, big ears and a body like a hoofed animal, now roam the grounds of Al Qudra Lakes, typically home to gazelle and other desert creatures of the United Arab Emirates. How they got there remains a mystery in the UAE, a country where exotic animals have ended up in the private homes and farms of the wealthy. But the pack appears to be thriving there and likely have survived several years already in a network of warrens among the dunes. Pilot dies in plane crash in remote woods of New York, puppy found alive WINDHAM, N.Y. (AP) — Authorities say a pilot and at least one dog he was transporting died when a small plane crashed in the snowy woods of the Catskill Mountains, though a puppy on the flight was found alive with two broken legs. The Greene County sheriff’s office says Seuk Kim of Springfield, Virginia, was flying from Maryland to Albany, New York, when the plane crashed at about 6:10 p.m. Sunday in a remote area. Officials believe the pilot died from the impact. The surviving dog was hospitalized, while a third dog was not located. The flight was connected with a not-for-profit group that transports rescue animals. New Zealanders save more than 30 stranded whales by lifting them on sheets WELLINGTON, New Zealand (AP) — More than 30 pilot whales that stranded themselves on a beach in New Zealand have been safely returned to the ocean after conservation workers and residents helped to refloat them by lifting them on sheets. New Zealand’s conservation agency said four whales died. New Zealand is a whale stranding hotspot and pilot whales are especially prolific stranders. The agency praised as “incredible” the efforts made by hundreds of people to help save the foundering pod. A Māori cultural ceremony for the three adult whales and one calf that died in the stranding took place Monday. Rainbow-clad revelers hit Copacabana beach for Rio de Janeiro’s pride parade RIO DE JANEIRO (AP) — Thousands of revelers have gathered alongside Copacabana beach for Rio de Janeiro’s annual gay pride parade, many scantily dressed and covered in glitter. Rainbow-colored flags, towels and fans abounded among the crowd mostly made up of young revelers, who danced and sang along to music blaring from speakers. While the atmosphere was festive, some spoke of the threat of violence LGBTQ+ people face in Brazil. At least 230 LGBTQ+ Brazilians were victims of violent deaths in 2023, according to the umbrella watchdog group Observatory of LGBTQ+ deaths and violence in Brazil.
ANKARA, Turkey (AP) — Turkey on Friday ousted two more elected pro-Kurdish mayors from office and replaced them with state-appointed administrators, citing terrorism-related charges against them. Read this article for free: Already have an account? To continue reading, please subscribe: * ANKARA, Turkey (AP) — Turkey on Friday ousted two more elected pro-Kurdish mayors from office and replaced them with state-appointed administrators, citing terrorism-related charges against them. Read unlimited articles for free today: Already have an account? ANKARA, Turkey (AP) — Turkey on Friday ousted two more elected pro-Kurdish mayors from office and replaced them with state-appointed administrators, citing terrorism-related charges against them. With their ouster, the number of elected mayors that have been sacked since October rose to six. An Interior Ministry statement said the mayor of the mainly Kurdish-populated provincial capital of Tunceli was removed from office due to his past conviction and an ongoing investigation for links to the banned Kurdistan Workers’ Party, or PKK. The district mayor for Ovacik, in Tunceli province, was sacked due to his past conviction of membership in the PKK, the statement said. The two mayors belong to the pro-Kurdish Peoples’ Equality and Democracy Party, or DEM, which is the third-largest party represented in Parliament. They were elected to office in local elections in March. Among those previously ousted was the mayor of Esenyurt, a district in Istanbul, who is a member of the main opposition Republican People’s Party, CHP. The mayor, Ahmet Ozer, was arrested last month, for alleged connections to the PKK. Several other pro-Kurdish mayors have similarly been ousted from office following past elections. President Recep Tayyip Erdogan’s government has defended the mayors’ removals saying they are part of efforts to maintain security. Opposition parties and human rights groups, however, accuse the government of undermining democracy and say the charges brought against the mayors are often politically motivated. The PKK, which has led an armed insurgency against the Turkish state since the 1980s, is designated a terrorist organization by Turkey, the United States and the European Union. The conflict has killed tens of thousands of people. AdvertisementHealthcare-focused AI startups are raising billions to help improve the US system. AI can help streamline clinical documentation, drug research, and medical billing. This article is part of "Trends in Healthcare," a series about the innovations and industry leaders shaping patient care. Get the inside scoop on today's big stories - delivered daily . Thanks for signing up! Look out for your first newsletter with today's big story in your inbox soon. Thanks for signing up! Access your favorite topics in a personalized feed while you're on the go. Download the app Email address Sign up By clicking “Sign Up”, you agree to receive emails from Business Insider. In addition, you accept Insider's Terms of Service and Privacy Policy . The founder of Suki, a startup that uses artificial intelligence to automate healthcare documents, raised $70 million in funding from investors in a Series D round that was disclosed this past fall. He said it really didn't take that much persuading: With an epidemic of stressed- and burned-out physicians, there was an obvious need for their AI software, he added. "Most of the investor conversations over the last year and a half have been, 'Well, it looks like the market is here,'" said Punit Singh Soni, Suki's founder. "Are you going to be the winner or not?" Suki sells an AI-powered assistant that takes notes during a conversation between patients and clinicians. The notes can be reviewed by the doctor and submitted as an electronic health record. This saves time on administrative tasks and allows physicians more time to take care of patients, a resource that's becoming increasingly limited among healthcare professionals. Surveys have consistently found that doctors and other medical workers are burned out from working in an often overloaded, convoluted, and inefficient system. The US spent $4.8 trillion on healthcare in 2023, according to a January report from the Peter G. Peterson Foundation. The US also spends more per person than nearly all other developed nations, according to a report by the Organization for Economic Co-operation and Development. Despite this, health outcomes were poorer, with Americans facing a lower life expectancy, higher rates of treatable and preventable excess deaths, and less efficient healthcare systems. Cash-strapped hospitals and private practices have lagged behind the financial-services and telecommunications industries in applying newer technologies, but the healthcare industry is increasingly considering artificial intelligence as it contends with high labor costs and a lot of opportunities to automate routine tasks. The pandemic exacerbated these challenges with staffing shortages as overworked doctors and nurses quit the profession. To make healthcare more efficient, AI startups like Suki, Zephyr AI, and Tennr have raised millions with vast promises, including making repetitive tasks like billing and note-taking easier, improving the accuracy of clinical diagnosis, and identifying the right patient population for emerging treatments. But the challenges are vast. The healthcare industry's budget allocations for generative AI are trailing those of many other core industries , such as energy and materials, consumer goods, and retail. Clinical diagnosis will continue to require a human in the loop, so the process can't be fully automated. The healthcare industry is highly regulated, and quite often, venture capitalists will wait for clarity on laws from the federal government before aggressively pushing AI tech advancements forward. A $370 billion bet on boosting the healthcare sector's productivity The consulting firm McKinsey estimates that generative AI can boost productivity for the healthcare, pharmaceuticals, and medical-products industries by as much as $370 billion by accelerating drug research, making clinical documentation easier, speeding up medical billing, and helping doctors make diagnoses. Some big funding rounds announced in 2024 highlight the diverse use cases for AI in the healthcare sector. They include $150 million raised by the clinical-documentation AI startup Abridge in February, the drug-discovery AI startup Xaira Therapeutics bringing in $1 billion before its launch in April, Atropos Health's $33 million Series B in May to help doctors analyze real-world evidence with generative AI, and the medical-billing-automation provider Candid Health raising $29 million in September. Parth Desai, a partner at Flare Capital Partners, has steered investments into healthcare startups such as Photon Health and SmarterDx. He said that healthcare organizations had been dedicating more money to bolster their AI strategies, beginning in late 2022 and accelerating through 2024. That's boosting demand for the tools these startups are developing. There's also less pressure to immediately prove a return on investment, which budget-conscious health systems have closely monitored in the past when allocating dollars for technology. "The thing that we're really studying before making an investment decision is: Do budgets exist today to pay for this technology?" Desai told Business Insider. "Or are they going to exist in a large-enough fashion in the next five to 10 years to support this technology?" Candid Health and Akasa aim to cut costs and automate medical billing One area of particular promise has been medical billing, which could benefit from large language model automation. An LLM could, for example, analyze a large volume of claims in a client's system and accurately match them with insurers' unique billing codes, a process required for repayment to a physician for their services. Hospitals have traditionally relied on human medical coders to hunt down reimbursements from insurers. "The software used to do billing was built a long time ago and basically wasn't kept up to date," Nick Perry, a cofounder and the CEO of Candid Health, said. Malinka Walaliyadde, the CEO of Akasa — another medical-billing-focused AI startup — said the company builds customized LLMs for each healthcare institution it serves. Typically, the aim for these LLMs is to lower costs by lessening the reliance on human medical coders. This often reduces errors in billing and speeds up repayment cycles. "We looked at what are the biggest pain points for health systems," Walaliyadde told BI. He said that Akasa's focus is on developing LLM products for medical coding and simplifying prior authorization, a process that requires approval from a health-plan provider before a patient can receive a treatment. "Those are the ones where you could really move the needle," Walaliyadde said. AI for health screenings George Tomeski, the founder of Helfie AI, is in the middle of pitching investors to raise as much as $200 million in a new round of funding that he hopes to close by the first half of 2025. Tomeski said the funding would help Helfie scale as it exits beta testing for the company's app. The app, also called Helfie, uses a smartphone camera to do medical "checks" that screen for illnesses including COVID-19, tuberculosis, and certain skin conditions. "We're targeting all the health conditions that lead to avoidable mortality," Tomeski said, adding that the app focuses on respiratory and cardiovascular conditions. The intention is for these checks —which can cost as low as $0.20 a person per screen — to serve as a form of preventive care and as an incentive to go see a doctor in person. While some funding is going toward sales and marketing, talent acquisition, and ensuring adherence to regulations around privacy and healthcare data, a large chunk is still being allocated to product development as AI tech advances quickly. Dr. Brigham Hyde, a cofounder and the CEO of Atropos Health, said his latest funding announcement, in May, was timed to coincide with the geared-up launch of ChatRWD, an AI copilot that can answer doctors' questions and quickly churn out published studies based on healthcare data. Hyde said he's keen to bring in big partners this time, including the pharmaceutical giant Merck and the medical-supplies and equipment maker McKesson. But Hyde also had to show some restraint. He said that when Atropos Health moved forward with its Series B rounds, dozens of venture capitalists expressed interest in leading the round. The company was offered up to $100 million but took only one-third of that amount. "I don't always think that's a good idea," Hyde told BI. "As a founder, you want to raise the right amount of money for your business and for the stage you're at." It may be tempting to take more, as many healthcare AI startups — a vast majority still in the seed and early-stage funding rounds — are racing to outmaneuver rivals. Even if the technology is right, it has to get past regulatory approvals and persuade cautious hospitals and health systems to open up their wallets. "You can build as much product as you want, but you can never build a market," Soni of Suki said. "It shows up, or it doesn't show up."
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